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Foot exercises show promise for diabetic nerve pain relief

NCT ID NCT05670600

Symptom relief Sponsor: Gazi University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a set of foot and ankle exercises could reduce pain and improve quality of life in 100 people with painful diabetic neuropathy. Participants performed exercises like ankle circles, toe spreads, and rolling a warm bottle under the foot. Researchers measured pain levels and quality of life at 4 and 8 weeks to see if the exercise group improved more than those who did not exercise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
foot and ankle exercises
What this could lead to
If effective, these simple exercises could offer a drug-free way to ease pain and improve daily life for people with diabetic neuropathy.
What could go wrong
This is a small, completed study without a placebo control, so results may not be widely applicable. Exercise might not help everyone and could cause temporary discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Jul 2021

Finished

Mar 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years and over, * Having been diagnosed with Type 2 diabetes for at least one year, * Diagnosed with diabetic peripheral neuropathy for at least 6 months by EMG by a neurologist, * Individuals with diabetes mellitus with neuropathic pain who score 12 or higher on the S-Lanns (Self-Leeds Assessment of Neuropathic Symptoms and Sign) pain scale, * Visual Analogue Scale (VAS) value to be at least 1, * Receiving medical treatment for diabetic neuropathy, * Did not receive physical therapy and non-pharmacological treatment during the research period, * Having no physical and mental problems that will prevent communication, * Having blood glucose meters at home, * Individuals with smart device use, Exclusion Criteria: * Peripheral vascular complications due to diabetes or another etiology, * Having a history of surgery on the knee, ankle and hip and indication for surgery during the intervention period, * Those who cannot communicate on the phone (with hearing problems), * Having nephropathy, retinopathy and diabetic foot, * Neurological diseases (stroke, cerebrovascular diseases, epilepsy) and serious musculoskeletal problems (rheumatoid arthritis, osteoarthritis) * Neurocognitive disorder (Alzheimer's disease, dementia), * Not taking any physical therapy during the intervention period, * Patients with deep vein thrombosis, femur fractures, surgical conditions, open wounds

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Conditions

The condition(s) this trial relates to.

diabetic neuropathy Motor Activity Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetic neuropathy, painful

Contacts and locations

Locations

  • Toros Devlet Hastanesi

    Mersin, Turkey (Türkiye)

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