Could a simple drink ease Parkinson's constipation?
NCT ID NCT06697626
First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 2 times
Summary
This study tests a new functional drink made with chicory inulin, B-vitamins, and vitamin D to see if it can improve constipation and overall well-being in people with Parkinson's disease. About 56 participants will drink either the active supplement or a placebo twice daily for 12 weeks. Researchers will measure changes in diet, gut health, Parkinson's symptoms, and quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- A functional drink containing chicory inulin, folic acid, vitamin B12, vitamin B6, riboflavin, and vitamin D
- What this could lead to
- If it works, this could provide a simple dietary supplement to help manage constipation and improve nutrition and quality of life for people with Parkinson's.
- What could go wrong
- This is a small, early feasibility study with only 56 participants, so results may not apply widely. The drink may not significantly improve symptoms or could cause digestive discomfort.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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37 people
The number who actually took part.
- Started
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Nov 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of Parkinson Disease (PD) * Aged ≥18 years * Individuals with the capacity to provide informed consent Exclusion Criteria: * Individuals with PD living in institutional care or in hospital * Drug, infection or toxin induced parkinsonism * Individuals with diabetes * B12 injection users * Currently taking antibiotics * Using supplements containing the nutrients of interest (B-vitamins, inulin, probiotics) * Any other medical, cognitive or psychosocial issue, or co-enrolment in another study, that could interfere or disrupt adherence to the study requirements * An allergy to any of the ingredients in the functional and/or control drinks * Consuming a fermented food and/or probiotic yogurts on a daily basis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Human Intervention Studies Unit, Ulster University
Coleraine, County Londonderry, BT52 1SA, United Kingdom
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