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Could a simple meal change ease stomach troubles for kids on tumor drug?

NCT ID NCT05101148

Summary

This study is testing whether taking the drug selumetinib with a low-fat meal is easier on the stomach than taking it on an empty stomach for teenagers with neurofibromatosis type 1 (NF1) and inoperable tumors. Researchers want to see if eating first reduces common side effects like nausea and diarrhea without making the drug less effective. The goal is to find the best way to take this already-approved medication to improve comfort and adherence.

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Contacts and locations

Locations

  • Research Site

    Rochester, Minnesota, 55905, United States

  • Research Site

    Akron, Ohio, 44308, United States

  • Research Site

    Bydgoszcz, 85-094, Poland

  • Research Site

    Gdansk, 80-952, Poland

  • Research Site

    Warsaw, 02-091, Poland

  • Research Site

    Moscow, 119620, Russia

  • Research Site

    Moscow, 125412, Russia

  • Research Site

    Barcelona, 08950, Spain

  • Research Site

    Madrid, 28009, Spain

Conditions

Explore the condition pages connected to this study.