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Scientists dig deeper into follicular lymphoma genes

NCT ID NCT05816850

Knowledge-focused Sponsor: Fondazione Italiana Linfomi - ETS Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study analyzes stored blood and tissue samples from 654 people with follicular lymphoma to learn how certain genetic changes affect the disease. Researchers are focusing on a gene called EZH2 and other biomarkers. The goal is to better understand the disease, not to test a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 654 people

The number the study aims to enrol. It can still change while the study runs.

Started

Sep 2023

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient affected by advanced Follicular Lymphoma treated with immunochemotherapy in the FIL\_FOLL12 trial

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient enrolled in the FIL\_FOLL12 trial (documented by the signature of the study informed consent); * Availability of biological samples: bone marrow aspirate, peripheral blood and/or FFPE diagnostic sample (nodal or extranodal); Exclusion Criteria: * None

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Get notified about this study

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Conditions

The condition(s) this trial relates to.

follicular lymphoma lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Follicular lymphoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    26 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • A.O. C. Panico, U.O.C Ematologia e Trapianto

    NOT_YET_RECRUITING

    Tricase, Italy

  • A.O. Ospedali Riuniti Villa Sofia-Cervello, Divisione di Ematologia

    RECRUITING

    Palermo, Italy

  • A.O. S. Croce e Carle, S.C. di Ematologia e Trapianto di Midollo Osseo

    NOT_YET_RECRUITING

    Cuneo, Italy

  • A.O. SS. Antonio e Biagio e Cesare Arrigo, S.C. Ematologia

    RECRUITING

    Alessandria, Italy

  • A.O.U. Città della Salute e della Scienza di Torino, Ematologia Universitaria

    RECRUITING

    Torino, Italy

  • A.O.U. Città della Salute e della Scienza di Torino, S.C. Ematologia

    RECRUITING

    Torino, Italy

  • AOU Maggiore della Carità di Novara, SCDU Ematologia

    RECRUITING

    Novara, Italy

  • ASST Grande Ospedale Metropolitano Niguarda, SC Ematologia

    RECRUITING

    Milan, Italy

  • ASST Spedali Civili di Brescia - Ematologia

    RECRUITING

    Brescia, Italy

  • Azienda Ospedaliera Universitaria Careggi - Unità funzionale di Ematologia

    NOT_YET_RECRUITING

    Florence, Italy

  • Azienda Ospedaliera Universitaria Policlinico - S. Marco, UOC di Ematologia

    RECRUITING

    Catania, Italy

  • Azienda Ospedaliero-Universitaria Policlinico di Modena, U.O. Oncologia

    RECRUITING

    Modena, Italy

  • Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), SOC Clinica Ematologica

    RECRUITING

    Udine, Italy

  • Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Ematologia

    RECRUITING

    Milan, Italy

  • Fondazione IRCCS San Gerardo dei Tintori - Ematologia

    RECRUITING

    Monza, Italy

  • Grande Ospedale Metropolitano Bianchi Melacrino Morelli - Ematologia

    NOT_YET_RECRUITING

    Reggio Calabria, Italy

  • IRCCS Istituto Romagnolo per lo studio dei Tumori "Dino Amadori" - IRST S.R.L., Ematologia

    RECRUITING

    Meldola, Italy

  • IRCCS Policlinico S. Matteo di Pavia, Divisione di Ematologia

    NOT_YET_RECRUITING

    Pavia, Italy

  • Istituto Clinico Humanitas, U.O. Ematologia

    RECRUITING

    Rozzano, Italy

  • Nuovo Ospedale degli Infermi, SSD Ematologia

    RECRUITING

    Biella, Italy

  • Ospedale Guglielmo da Saliceto, U.O. Ematologia

    RECRUITING

    Piacenza, Italy

  • Ospedale Policlinico San Martino S.S.R.L. - IRCCS per l'Oncologia, Ematologia e terapie cellulari

    RECRUITING

    Genova, Italy

  • Ospedale degli Infermi di Rimini, U.O. di Ematologia

    NOT_YET_RECRUITING

    Rimini, Italy

  • Ospedale di Circolo - U.O.C Ematologia

    NOT_YET_RECRUITING

    Varese, Italy

  • Policlinico Umberto I - Università "La Sapienza", Istituto Ematologia -Dipartimento di Medicina Traslazionale e di Precisione

    RECRUITING

    Roma, Italy

  • Presidio ospedaliero "A. Tortora", U.O. Onco-ematologia

    RECRUITING

    Pagani, Italy

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Other studies related to the condition(s) this trial covers.