IVF egg hunt: does flushing follicles boost harvest?
NCT ID NCT07335016
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether rinsing (flushing) ovarian follicles during egg retrieval can increase the number of mature eggs collected for IVF. In 75 women undergoing IVF, one ovary will be flushed and the other will not, and the egg yields will be compared. The goal is to see if this simple technique improves IVF outcomes.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- follicular flushing
- What this could lead to
- If successful, this could show that follicular flushing improves egg yield during IVF, potentially leading to better success rates for some patients.
- What could go wrong
- This is a small, early-stage study (75 participants) comparing two techniques within the same patient. Results may not apply broadly, and any benefit might be modest or absent.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 75 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 46 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ovarian stimulation with recFSH and GnRH antagonist or PPOS protocol * Triggering final oocyte maturation with hCG or GnRH agonist * The day of oocyte retrieval at least one follicle of mean diameter of 11mm in each ovary * ICSI method of fertilisation. Exclusion Criteria: * Presence of ovarian cyst of endometriosis * History of ovarian surgery * Monofollicular growth * Presence of only one ovary * Ovary not accessible at oocyte retrieval
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Aristotle University of Thessaloniki
Thessaloniki, Greece
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Eugonia IVF
Athens, Greece
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