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Could a cheaper hormone make IVF more affordable?

NCT ID NCT07771283

Disease control Sponsor: LTD "EKODNIPRO", Medical centre Medical Plaza Dnipro Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 18, 2026 · Last updated Aug 28, 2026 · Updated 3 times

Summary

This trial is testing whether a more affordable hormone protocol can work as well as standard IVF stimulation. Typically, IVF uses expensive gonadotropins to stimulate the ovaries to produce multiple eggs. The study compares a protocol that replaces a large portion of these with human chorionic gonadotropin (hCG) against standard protocols. Researchers will compare the number and quality of eggs and embryos, as well as pregnancy and live birth rates, to see if the cheaper approach is just as effective and safe.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Human chorionic gonadotropin (hCG) used as a substitute for part of the standard gonadotropin stimulation in IVF
What this could lead to
If effective, this could make IVF more affordable by reducing the need for expensive gonadotropin medications, potentially expanding access to fertility treatment.
What could go wrong
The trial is early and may show that hCG is less effective than standard protocols. There is also a risk of ovarian hyperstimulation syndrome (OHSS), though the study monitors for this.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 360 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women of reproductive age between 18 and 40 years. * Clinical indications for the induction of superovulation (undergoing ART/IVF programs). * Patients with all variants of ovarian reserve. * Body Mass Index (BMI) up to 35 kg/m². * Provision of informed consent to participate in the research study. Exclusion Criteria: * Presence of ovarian endometriomas. * History of severe Ovarian Hyperstimulation Syndrome (OHSS) in previous cycles. * Presence of severe endocrine disorders. * History or presence of oncological diseases. * Any medical contraindications to hormonal stimulation. * Severe male factor infertility (specifically cryptozoospermia)

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Conditions

The condition(s) this trial relates to.

female infertility infertility disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Controlled ovarian simulation Infertile patients Infertile women undergoing art Infertile women undergoing assisted reproductive technology (ART) Infertile women undergoing ivf or icsi Infertility Infertility (ivf patients) Infertility assisted reproductive technology Infertility drugs Stimulation in the ovary

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    3 sites in 2 countries. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • LTD "EKODNIPRO" Medical Centre "Medical Plaza"

    Dnipro, Ukraine

  • LTD "Yuzko" Yuzko Medical Center

    Chernivtsi, Ukraine

  • Sali international school of fertility medicine

    Kampala, Uganda

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