Sound waves vs. Parkinson's: could ultrasound ease early symptoms?
NCT ID NCT06584383
First seen Jan 22, 2026 · Last updated Jun 23, 2026 · Updated 27 times
Summary
This study tests a non-invasive procedure called focused ultrasound on people with early-stage Parkinson's disease. It uses sound waves to target a small area in the brain involved in movement. The goal is to see if this treatment improves motor symptoms better than standard medication alone. About 67 participants will be randomly assigned to receive either the ultrasound procedure or continue with their usual medical care.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Clinica Universidad de Navarra
Pamplona, 31008, Spain
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HM CINAC- Hospital Universitario HM Puerta del Sur
Móstoles, 28938, Spain
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Pontificia Universidad Catolica de Chile
Santiago, Chile
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Universitätsklinikum Schleswig-Holstein, Campus Kiel (UKSH)
Kiel, 24105, Germany
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Exablate MR-guided focused ultrasound (MRgFUS) subthalamotomy
What this could lead to
If successful, this could offer a non-invasive treatment option to reduce motor symptoms in early-stage Parkinson's disease, potentially delaying the need for stronger medications.
What could go wrong
This is an early-stage study with only 67 participants, so results may not apply to everyone. The procedure targets one side of the brain and may not address all symptoms, and there are risks like brain swelling or movement issues.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.