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Vibrating muscles while exercising could rewire the brain to ease chronic shoulder pain

NCT ID NCT06694402

Symptom relief Sponsor: National Yang Ming Chiao Tung University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study investigates whether adding focal muscle vibration to shoulder exercises can improve how the brain processes sensory and movement signals in people with chronic subacromial impingement syndrome. Participants will receive 12 sessions of either vibration-assisted exercise or exercise alone. Researchers will measure brain activity, pain, and shoulder function to see if the vibration boosts the benefits of exercise.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
focal muscle vibration combined with exercise
What this could lead to
If it works, this approach could offer a new, non-drug way to improve shoulder function and reduce pain in people with chronic shoulder impingement.
What could go wrong
This is a small, early-stage trial with only 28 participants, so results may not apply to everyone. The vibration device may not provide added benefit over exercise alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

28 people

The number who actually took part.

Started

Jan 2025

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Anterior or lateral shoulder pain ≥ 3 months 2. 18 to 65 years old 3. The most pain intensity ≥ 3/10 Pain-Numeric Scale (NRS) 4. SIS, at least 3 positive findings of the following tests: (1) Neer's test (2) Hawkins-Kennedy test (3) Empty can test (4) Resisted external rotation test (5) Presenting painful arc during arm elevation (6) Tenderness of the rotator cuff tendons Exclusion Criteria: 1. History of dislocation, fracture, adhesive capsulitis or surgery of upper extremity 2. Neck pain 3. Shoulder flexion or abduction less than 150 degrees 4. History of direct contact injury to the neck or upper extremities within the past 12 months 5. Brain injury and neurological impairment 6. Inflammatory cause of the pain (e.g., rheumatoid arthritis) 7. Psychosis and symptom of headache or dizziness 8. Taking centrally acting medication 9. Contraindications to the use of transcranial magnetic stimulation (TMS) 10. Received shoulder-related physical therapy or corticosteroid injections in the past three months. 11. Received high-concentration platelet-rich plasma (PRP) injections in the shoulder joint in the past year.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome shoulder impingement syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain Chronic subacromial impingement syndrome Corticomotor excitability Electroencephalography Focal vibration Intracortical inhibition Somatosensory dysfunction Transcranial magnetic stimulation

Contacts and locations

Locations

  • National Yang Ming Chiao Tung University

    Taipei, 112, Taiwan

More trials for these conditions

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