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Sound waves vs. prostate cancer: new procedure aims to destroy tumors without surgery

NCT ID NCT05438563

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This trial tests a procedure called MRI-guided TULSA for men with low to intermediate grade prostate cancer. It uses high-energy sound waves guided by MRI to precisely heat and destroy tumor cells. The goal is to control the cancer while avoiding surgery and preserving quality of life, such as urinary continence and sexual function. About 100 men aged 45 to 80 with early-stage prostate cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mayo Clinic in Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MRI-guided transurethral ultrasound ablation (TULSA)

What this could lead to

If successful, this could offer a less invasive treatment option for prostate cancer that avoids surgery and reduces side effects like incontinence and impotence.

What could go wrong

This is an early-stage trial with only 100 participants. The procedure may not control the cancer long-term, and some men may still need additional treatments.

Conditions

The condition(s) this trial relates to.

prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.