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Smart hydration during surgery may shield Seniors' brains

NCT ID NCT07438249

Knowledge-focused Sponsor: Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 180 older adults (65+) having major abdominal cancer surgery to see if giving fluids based on real-time body signals (goal-directed fluid therapy) helps prevent short-term memory and thinking problems after surgery. Patients received either this personalized approach or standard care. The main goal was to compare changes in thinking test scores from before surgery to one and seven days after. The study aims to find better ways to support brain health during surgery in elderly patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

180 people

The number who actually took part.

Started

Dec 2024

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of geriatric patients (aged 65 and older) scheduled for elective major abdominal cancer surgery at the University of Health Sciences, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital. Participants will be selected from patients who meet the inclusion criteria and provide informed consent during their preoperative evaluation in the anesthesiology clinic

Ages

65 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 65 years (geriatric patients) * Scheduled for elective major abdominal cancer surgery * American Society of Anesthesiologists (ASA) Physical Status I-IV * Eastern Cooperative Oncology Group (ECOG/WHO/Zubrod) performance status ≥ 2 * Ability to complete cognitive assessments * Provision of written informed consent Exclusion Criteria: * Severe cardiac dysfunction (Cardiac Index ≤ 2.2 L/min/m²) * History of neurological or psychiatric disorders (e.g., dementia, Alzheimer's disease) * Use of medications that significantly affect cognitive function * Severe hepatic or renal failure * Prior chemotherapy or radiotherapy before surgery * Intraoperative or perioperative blood transfusion * Prolonged mechanical ventilation (inability to extubate immediately after surgery) * Pre-existing cognitive impairment (baseline Mini-Mental State Examination \[MMSE\] score \< 24)

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Conditions

The condition(s) this trial relates to.

Abdominal Neoplasms neoplasm Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Abdominal neoplasm Geriatrics Hemodynamics Postoperative cognitive dysfunction

Contacts and locations

Locations

  • Dr. Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital Clinic of Anesthesiology and Rea

    Ankara, Yenimahalle, 06200, Turkey (Türkiye)

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