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Fingertip test could guide sepsis treatment, small study suggests

NCT ID NCT06067516

Knowledge-focused Sponsor: Samsun University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study in 44 intensive care patients with sepsis or septic shock examined how giving standard IV fluids affects capillary refill time (a simple fingertip test) and organ function. Researchers measured changes in organ failure scores and stroke volume after fluid resuscitation. The goal was to see if capillary refill time can help guide fluid therapy in sepsis.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
crystalloid fluid (standard IV fluids)
What this could lead to
If successful, this could help doctors use a simple fingertip test to guide fluid treatment in sepsis, potentially improving organ recovery.
What could go wrong
This is a small, completed observational study with only 44 patients, so results may not apply broadly. It does not test a new drug or treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

44 people

The number who actually took part.

Started

Oct 2023

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients admitted to intensive care due to sepsis and septic shock.

Ages

18 to 90 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Over 18 years old * Admitted to intensive care with a diagnosis of sepsis or septic shock * Systolic blood pressure \< 90 mmHg or Mean blood pressure \< 65 mmHg * Those who need vasopressor medication * Urine output \< 0.5 ml/kg/h for at least two hours * Tachycardia (Heart rate \> 100/min) * Serum Lactate \> 2 mmol/L * Patients with central venous oxygen saturation (ScvO) \< 70% Exclusion Criteria * Not approved by the patient or his/her guardian * Known heart, kidney, liver failure * The initial cause of shock is neurogenic, cardiogenic or obstructive shock. * Pregnancy or suspected pregnancy * Those with amputation or severe organ ischemia * Those with peripheral artery disease * Cannot be evaluated optimally with transthoracic echo * Patients who died in the first 24 hours

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Conditions

The condition(s) this trial relates to.

infectious disease with sepsis Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sepsis

Contacts and locations

Locations

  • Samsun University

    Samsun, Ilkadim, 55090, Turkey (Türkiye)

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