New Fluid-Guiding tech tested in prostate surgery to prevent complications
NCT ID NCT07669337
First seen Jun 27, 2026 · Last updated Jul 08, 2026 · Updated 2 times
Summary
This study compares standard fluid management to a newer method using the Plethysmography Variability Index (PVI) during prostate surgery for enlarged prostate. The goal is to see if PVI-guided care reduces risks like fluid overload or low blood pressure. Fifty-eight men aged 50-80 will be randomly assigned to one of the two approaches.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Plethysmography Variability Index (PVI)-guided goal-directed fluid management
- What this could lead to
- If successful, this could lead to a safer, more precise way to manage fluids during prostate surgery, reducing complications like fluid overload or low blood pressure.
- What could go wrong
- This is a small, early-stage trial with only 58 participants, so results may not apply to all patients. The technique may not show clear benefits over standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 58 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Mar 2016
- Expected to finish
-
Feb 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 80 years
- Sex
-
Male participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * • Male patients aged from 50 to 80 years Scheduled for elective TURP. * ASA Ⅰ, Ⅱ. Exclusion Criteria: * • Cardiac arrhythmias (e.g., atrial fibrillation) * Left ventricular ejection fraction \<40% * Chronic kidney disease (stage ≥ 3) * Hepatic dysfunction * Peripheral vascular disease * Prolonged procedures more than 2 hours or complicated procedures with severe bleeding affecting management (Severe bleeding will be defined as any of the following: a drop in hemoglobin of ≥ 2 g/dl, hemodynamic instability due to blood loss that requires blood transfusion). * Patients refuse to share in this study.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Benign prostatic hyperplasia (BPH) requiring surgical resection are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Cairo University Hospitals Anesthesia Department
Cairo, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.