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Pre-Surgery fluid infusion may cut Post-Op complications

NCT ID NCT05728645

Disease control Sponsor: Xijing Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether giving fluids (colloids or crystalloids) before general anesthesia can prevent low blood pressure and reduce complications within 30 days after non-cardiac surgery. Over 2,000 adults having elective surgery took part. The goal was to see if this simple step could improve recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

2,022 people

The number who actually took part.

Started

Jul 2023

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 18 years or older * ASA I-III * Undergoing elective non-cardiac surgery under general aneathesia Exclusion Criteria: * Allergic to colloids * Severe heart diseases ( Ejection Fraction lower than 35%) * Presence of renal failure pre-operatively (defined as eGFR \< 30 mL/min/1.73 m2 and/or patient receiving renal replacement therapy) * Morbid obesity (BMI \> 37.5kg/m2 or \> 32.5kg/m2 with metabolic diseases) * Presence of a coagulopathy at screening (defined as platelet count \< 100 × 109/L and/or a prothrombin time \< 70% and/or an activated partial thromboplastin time (aPTT) \>35 s and/or fibrinogen \<1 g/ L) * Presence of liver injury (defined as Child-Pugh C) * Pre-operative electrolyte disturbances with Na \>160 mmol/L or \<120 mmol/L * Patients with preoperative intracranial hypertension requiring dehydration treatment

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Conditions

The condition(s) this trial relates to.

Postoperative Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative complications

Contacts and locations

Locations

  • Xijing Hospital

    Xi'an, Shaanxi, 710032, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.