Which pill works best for tough ringworm? new study aims to find out
NCT ID NCT07342153
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two common oral antifungal pills—fluconazole and itraconazole—in adults with ringworm that hasn't cleared up with creams. 126 people aged 18-70 with persistent infection for at least 6 months will be randomly assigned to one of the two drugs for 4 weeks. The goal is to see which one completely clears the rash, itching, and scaling.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- fluconazole and itraconazole (oral antifungal drugs)
- What this could lead to
- If this trial succeeds, it could help doctors choose the most effective oral antifungal for stubborn ringworm infections, improving treatment success and quality of life.
- What could go wrong
- This is a small, single-center Phase 4 trial. Results may not apply to all populations, and neither drug may work well for everyone with resistant infections.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 126 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adults aged 18-70 years Male or female Clinical diagnosis of resistant tinea corporis, defined as persistent disease ≥6 months despite topical antifungal therapy Microscopic confirmation of fungal hyphae on KOH preparation of skin scrapings Exclusion Criteria: Prior use of oral antifungal therapy within the past 3 months Recent antibiotic treatment for superadded bacterial skin infection in the past 1 month Known immunosuppressive conditions (e.g., diabetes mellitus, malignancy) Current or recent use of immunosuppressive drugs Pregnant or lactating women
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Locations
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CDA Hospital Islamabad
RECRUITINGIslamabad, Punjab Province, 46000, Pakistan
Contact Email: •••••@•••••
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