Flu vaccine under the microscope: does it protect hospitalized patients?
NCT ID NCT01764152
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study looked at how well the seasonal flu vaccine worked during the 2012-2013 flu season in adults who were hospitalized with flu-like symptoms. Researchers compared vaccinated and unvaccinated patients across a network of French hospitals to see if the vaccine reduced confirmed flu cases. The goal was to measure vaccine effectiveness in a real-world hospital setting.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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450 people
The number who actually took part.
- Start date
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Dec 2012
- Finished
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May 2013
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 year * Affiliated with social security health insurance * Written informed consent * Patients hospitalized for 24 hours and presenting an influenza-like illness in the last 7 days before the hospitalization Exclusion Criteria: * Against indication for influenza vaccination(Hypersensitivity to the active substances, to any of the excipients and to trace eg eggs, including ovalbumin, chicken protein) * Patients institutionalized without regular community interaction * Patient already hospitalized for respiratory infection during the 2012-2013 influenza season * Flu already virologically documented in the current influenza season 2012-2013 (RT-PCR, multiple RT-PCR and / or culture.)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Institut National de la Santé Et de la Recherche Médicale
Paris, 75654, France