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New pill could shrink enlarged spleens in myelofibrosis patients

NCT ID NCT07317700

First seen Jan 09, 2026 · Last updated May 23, 2026 · Updated 29 times

Summary

This study tests a new drug called flonoltinib maleate in people with intermediate- or high-risk myelofibrosis, a rare bone marrow disorder. The main goal is to see if the drug can shrink the spleen by at least 35% and reduce symptoms like pain and fatigue. About 105 adults aged 18-80 will take either the new drug or an existing one, and researchers will compare results over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences (IHCAMS)

    RECRUITING

    Tianjin, Tianjin Municipality, 300052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital Sichuan University

    RECRUITING

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.