Fizzy drink study probes saliva secrets
NCT ID NCT06933290
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study investigates how flavored carbonated drinks change saliva flow, composition, and taste perception compared to plain water, carbonated water, or non-carbonated drinks. Healthy adults aged 18-45 who regularly drink carbonated beverages will provide saliva samples after tasting different drinks. The goal is to learn more about how these popular beverages affect the mouth and taste.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- flavored carbonated drinks
- What this could lead to
- If it works, this could help understand how carbonated beverages influence oral health and taste perception.
- What could go wrong
- This is a very small early-stage study with only 13 participants, so results may not apply broadly.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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13 people
The number who actually took part.
- Started
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Mar 2025
- Finished
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May 2025
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Subject is male or female * If female, subject is not pregnant or nursing (based on self-report) * Subject is 18-45 years of age, inclusive * Subject is a regular consumer of carbonated drinks (questionnaire) * Subject is willing to avoid alcohol consumption 24 hours prior to visits * Subject is willing to fast (no food or gum) for 2 hours prior to study sessions * Able to speak, write, and read English * Provision of written consent to participate Exclusion Criteria: * Subject smokes, vapes, or uses any nicotine/tobacco products (or has quit for less than 6 months) * Subject currently has or recently had an illness (cold, flu, COVID) within the past month * Subject has a condition affecting the oral cavity such as Xerostomia (dry mouth), Sores/lesions, Untreated dental caries, Major dental implants/appliances (including dentures) * Subject has a reduced sense of taste (dysgeusia) or smell (parosmia) * Subject has a health condition that would interfere with the study as indicated on the general health questionnaire (GHQ) (including cardiovascular, renal, or metabolic diseases) * Subject has participated in a clinical trial within the past 30 days * Subject has participated in any PepsiCo trial within past 6 months * Subject has a condition or is taking medication that the investigator believes would interfere with his/her ability to provide informed consent, comply with the study protocol, which might confound the interpretation of the study results, or put the person at undue risk * Subject is employed by, or has a parent, guardian, or other immediate family member employed by a company that manufactures any products that compete with any PepsiCo product. If subject is unsure if a company would be considered a competitor to PepsiCo, they will be asked to please let the study investigator know the name of the other company and the nature of their relationship to that company before they sign the informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Gatorade Sports Science Institute
Valhalla, New York, 10595, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.