Autosomal dominant medullary cystic kidney disease with or without hyperuricemia
MONDO:0008264A genetic kidney disease that causes progressive loss of kidney function caused by mutations in the genes encoding uromodulin (UMOD), hepatocyte nuclear factor-1β (HNF1B), renin (REN), or mucin-1 (MUC1).
Also known as: ADTKD, autosomal dominant interstitial kidney disease, autosomal dominant medullary cystic kidney disease, autosomal dominant medullary cystic kidney disease with or without hyperuricemia, MCKD, autosomal dominant tubulointerstitial kidney disease, medullary cystic disease, medullary cystic kidney disease
8 clinical trials for this condition and its sub-types, 7 tagged with Autosomal dominant medullary cystic kidney disease with or without hyperuricemia itself.
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Browse by category →Sub-types of Autosomal dominant medullary cystic kidney disease with or without hyperuricemia
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New antibody M0324 enters first human trials for Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage study is testing a new drug called M0324, a bispecific antibody designed to target cancer cells. The trial will look at M0324 alone, with the immunotherapy pembrolizumab, and with chemotherapy in about 77 people with advanced solid tumors that have not responded …
Phase 1 • Sponsor: EMD Serono Research & Development Institute, Inc. • Aim: Disease control
Last updated Sep 11, 2026 00:00 UTC
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Could a diabetes drug protect kidneys in children with genetic disease?
Disease control Recruiting nowThis study tests whether adding dapagliflozin (a diabetes drug) to standard care reduces protein leakage in the urine of children with hereditary kidney diseases. About 44 children will receive either dapagliflozin plus standard care or standard care alone for 12 weeks, then swit…
Phase 3 • Sponsor: Children's Hospital of Fudan University • Aim: Disease control
Last updated Jul 08, 2026 00:00 UTC