Flavor variety may boost quit rates in smokers switching to E-Cigs

NCT ID NCT07598136

Recruiting now Disease control Sponsor: RAI Services Company Source: ClinicalTrials.gov ↗

First seen May 27, 2026 · Last updated Jun 22, 2026 · Updated 3 times

Summary

This study tests whether giving smokers access to multiple e-cigarette flavors (like menthol, mint, or fruit) helps them stop smoking regular cigarettes. About 1,280 adult smokers will use a provided e-cigarette device for 13 weeks, with some getting only tobacco flavor and others getting a choice of flavors. The main goal is to see who stays away from cigarettes in the final week.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

L&E Raleigh
RECRUITING

Raleigh, North Carolina, 27612, United States
Sago Atlanta
RECRUITING

Atlanta, Georgia, 30328, United States
Sago Dallas
RECRUITING

Dallas, Texas, 75254, United States
Sago Houston
RECRUITING

Houston, Texas, 77027, United States
Sago Orlando
RECRUITING

Maitland, Florida, 32751, United States
Sago Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19103, United States
Sago St. Louis
RECRUITING

St Louis, Missouri, 63131, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

electronic nicotine delivery system (ENDS) with various e-liquid flavors

What this could lead to

If successful, this could show that offering a variety of flavors in e-cigarettes helps more smokers switch away from combustible cigarettes.

What could go wrong

This is a behavioral study, not a test of a new drug. Results may not apply to all smokers, and long-term health effects of e-cigarettes are still unknown.

Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Tobacco Smoking Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING TOBACCO