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New study tests best method to reduce pain after wisdom tooth surgery

NCT ID NCT07198282

Symptom relief Sponsor: Recep Tayyip Erdogan University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares four ways to close the gum after removing an impacted wisdom tooth: standard stitches, leaving the wound open, placing a small drain, or using medical glue. The goal is to see which method causes the least pain, swelling, and difficulty opening the mouth. About 148 healthy adults aged 18-40 are being recruited.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cyanoacrylate tissue adhesive
What this could lead to
If successful, this could identify the best closure technique to reduce pain, swelling, and jaw stiffness after wisdom tooth removal.
What could go wrong
This is a small, single-center trial comparing routine techniques, so results may not apply broadly. No major risks beyond standard oral surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 148 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2026

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-40 years. * Patients with no systemic diseases (ASA I). * Patients with impacted mandibular third molars indicated for extraction, with bone and/or mucosal retention, in similar positions (Pell \& Gregory Class 2, Position B; Winter classification vertical or mesioangular). Exclusion Criteria: * Patients classified as ASA II, III, or IV. * Known allergy to anesthetic solutions. * Allergy to acrylate. * Pregnant or breastfeeding women. * Individuals with tobacco use ≥10 cigarettes/day. * Alcohol users. * Patients using antiplatelet agents. * Patients using anticoagulants. * Patients with coagulation disorders. * Patients with immunosuppressive diseases or receiving immunosuppressive therapy. Patients with acute pain or local infection at the surgical site.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Impacted mandibular third molar Oral surgery Postoperative morbidity

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Recep Tayyip Erdoğan University, Faculty of Dentistry, Department of Oral and Maxillofacial Surgery

    RECRUITING

    Rize, Rize Province, Turkey (Türkiye)

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