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Inhaled bacteria protein could train lungs to fight pneumonia

NCT ID NCT06681402

First seen Apr 19, 2026 · Last updated Jun 23, 2026 · Updated 11 times

Summary

This early-stage trial tested a single inhaled dose of FLAMOD, a protein from bacteria, in 46 healthy adults. The goal was to see if it is safe and can activate the immune system in the lungs. Researchers are looking for the best dose that triggers immune responses without causing serious side effects. This is a first step toward possibly preventing pneumonia in the future.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre hospitalier régional universitaire de de Tours

    Tours, 37044, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

FLAMOD (flagellin, a protein from bacteria)

What this could lead to

If successful, this could point toward a new way to boost lung immunity and prevent pneumonia.

What could go wrong

This is a very early Phase 1 safety trial in only 46 healthy people. It does not test whether FLAMOD actually prevents pneumonia, and results may not apply to sick patients.

Conditions

The condition(s) this trial relates to.

pneumonia Respiratory Aspiration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.