Firefighters get cutting-edge cancer screening in new pilot study
NCT ID NCT06931561
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether whole-body MRI, ultrasound, and a new blood test can find cancer early in firefighters. Firefighters have a higher risk of certain cancers due to job exposures. The study will enroll 800 active firefighters aged 35 and older with at least 10 years of service. Results will show how well these screening tools detect pre-cancer and cancer.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 800 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2025
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 35 years old * at least 10 cumulative years working as a firefighter * Actively serving as a firefighter (active or volunteer) with completion of NFPA physical examination within the past 6 months * Ability to understand and willing to sign informed consent * Ability to understand and willing to sign the Health Insurance Portability and Accountability Act (HIPAA) Authorization * Additional eligibility criteria in protocol Exclusion Criteria: * No prior history of any invasive cancer within the previous 5 years (non-melanoma skin cancer and in situ carcinoma would still be eligible) and no current diagnostic workup for suspicion of cancer * Received a whole-body MRI, whole-body ultrasound, or been tested with a MCD within the past 1-year * For women of childbearing potential, pregnancy and no plans for pregnancy for the duration of the study * Additional exclusion criteria in protocol
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Inova Schar Cancer - Saville Cancer Screening and Prevention Center
RECRUITINGFairfax, Virginia, 22031, United States
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