Can a kidney drug stop acute injury from becoming chronic?

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adult patients (≥18 years old) at the time of giving consent * Admitted to the hospital at the time of giving consent * KDIGO Stage ≥2 AKI confirmed by at least two separate creatinine measurements (definition: ≥2.0 times baseline creatinine, no urine output criteria) * Sustained AKI criteria for ≥48 hours since AKI diagnosis * No AKI progression before randomization (as per the judgement of the investigator) * Serum potassium ≤4.8 mmol/L within 48 hours before randomization * Suspected intrinsic AKI (hemodynamic and obstructive AKI has been ruled out according to the judgment of the investigator) * Participant should be capable of giving signed informed consent, which includes compliance with the requirements and restrictions of the participating site Exclusion Criteria: * Planned hospital discharge within 48 hours * Any ongoing use of MRA (spironolactone, eplerenone, finerenone), potassium-sparing diuretics (such as triamterene or amiloride), or potassium binders * Advanced CKD defined as eGFR ≤30 mL/min/1.73m² or undergoing KRT at baseline * Ongoing KRT at the time of randomization (Stage 3-dialysed AKI that partially/completely recovered and no longer required KRT at randomization can be included) * Clinically unstable (based on investigator clinical evaluation, i.e., vasopressors, uncontrolled sepsis) * Confirmed or suspected glomerular disease (other than diabetes) or acute interstitial nephritis requiring immunosuppressive therapy as the primary cause of AKI * Previous hypersensitivity to finerenone * Documented history of adrenal insufficiency or Addison's disease * Concomitant therapy with strong CYP3A4 inhibitors, if conversion to another medication is not feasible * Clinician judgment that the intervention is contraindicated due to: A) risk of hyperkalemia; B) risk of KRT initiation within the next 7 days (anuria or rapid increase in serum creatinine); C) impossibility to administer potassium binders * Enrollment in another clinical trial that could impact potassium, GFR, or kidney function * For women who are able to become pregnant: positive pregnancy test and/or being breastfeeding at screening * Any other condition or therapy, in the judgement of the Investigator or the Sponsor, which could make the participant unsuitable for this study, including a condition or therapy which the Investigator anticipates will not allow participation for the full planned study period (i.e., condition limiting life expectancy to less than 3 months)