Massage or nerve stimulation: which eases fibromyalgia pain?
NCT ID NCT07425652
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two non-invasive treatments—connective tissue massage and vagus nerve stimulation—alone or together, in 66 women with fibromyalgia. The goal is to see if these methods improve pain, sleep, fatigue, and quality of life. Participants will be randomly assigned to one of three groups and followed for several weeks.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- connective tissue massage and transcutaneous auricular vagus nerve stimulation
- What this could lead to
- If successful, this could point toward effective non-drug options for managing fibromyalgia symptoms like pain and fatigue.
- What could go wrong
- This is a small, early-stage trial with only 66 participants, so results may not apply to everyone. The treatments may not provide significant relief.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 66 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Having been diagnosed with fibromyalgia * Being female between the ages of 18-65 * Volunteering to participate in the study Exclusion Criteria: * Diagnosed neurological and infectious diseases * Uncontrolled endocrine and/or autoimmune diseases * Serious psychiatric disorders (bipolar disorder, schizophrenia, psychosis, etc.) * Pregnancy or breastfeeding * Malignancy * History of known arrhythmia or any implanted electronic device * Presence of sensory loss * Acute inflammation, open wounds, erythema in massage areas * History of any surgery within the last 6 months * Having received physical therapy for FM within the last 6 months and/or being included in a new treatment program during the study period
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Gazi Mustafa Kemal Occupational and Environmental Diseases Hospital
RECRUITINGAnkara, 06560, Turkey (Türkiye)
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