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Bronchoscopy boost for ventilator pneumonia?

NCT ID NCT07149909

Disease control Sponsor: Benha University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested whether adding a procedure called fiberoptic bronchoscopy to standard care helps adults with severe ventilator-associated pneumonia. One hundred patients were split into two groups: one got usual treatment (antibiotics, suctioning), the other got the same plus daily bronchoscopy for a week. Researchers measured recovery, ICU stay, and survival to see if the extra procedure made a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fiberoptic bronchoscopy
What this could lead to
If successful, this could show that adding bronchoscopy to standard care helps clear infections faster and reduces ICU stays for patients with severe pneumonia on ventilators.
What could go wrong
This is a single-center trial with only 100 participants, so results may not apply to all patients. The procedure itself carries risks like bleeding or infection, and the benefit over standard care may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Dec 2023

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-65 years * Patients of both sexes * Patients requiring mechanical ventilation * Development of pneumonia ≥ 48 hours after endotracheal intubation or ≥ 48 hours after extubation * Diagnosis of severe ventilator-associated pneumonia defined by a Modified Clinical Pulmonary Infection Score (CPIS) \> 6 Exclusion Criteria: * Refusal to participate * Presence of lung shadows prior to mechanical ventilation * Severe bleeding disorders or immune system diseases * Severe hemodynamic instability * Recent myocardial infarction or unstable arrhythmia * Tracheal stenosis or upper airway mass

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Conditions

The condition(s) this trial relates to.

Critical Illness pneumonia Pneumonia, Ventilator-Associated respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Critical illness Severe pneumonia Ventilator associated pneumonia

Contacts and locations

Locations

  • Benha University

    Banhā, Benha, 13511, Egypt

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