Could a daily dose of fiber from thai jerusalem artichoke reshape gut bacteria and trim body fat in obese kids?
NCT ID NCT03968003
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study investigates whether a daily fiber supplement called inulin, extracted from Thai Jerusalem artichoke, can change the gut bacteria and reduce body fat in obese children aged 7 to 15. Over six months, one group receives inulin, another gets a placebo, and a third group receives dietary advice. Researchers will measure changes in gut microbes, body composition, and appetite-related hormones.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Inulin (a type of dietary fiber from Jerusalem artichoke)
- What this could lead to
- If it works, this could point toward a simple, natural way to improve gut health and body composition in obese children.
- What could go wrong
- This is an early-stage study with a modest sample size. Results may not apply to other populations, and the fiber supplement may cause digestive discomfort.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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165 people
The number who actually took part.
- Started
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Aug 2017
- Finished
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Jul 2020
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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7 to 15 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children, age 7 to 15 years * Body mass index (BMI) ≥ median + 2 Standard deviation (SD) Exclusion Criteria: * Underlying disease of syndromic obesity and monogenic obesity * Endocrine causes of obesity (e.g. hypothyroidism, growth hormone deficiency) * Use of drugs that influence appetite or body weight (e.g. corticosteroids) * Attending other concurrent weight reduction programs
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Chulalongkorn University
Bangkok, 10330, Thailand
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