Umbilical cord patch could fix spina bifida in the womb
NCT ID NCT04243889
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 31 times
Summary
This study tests a patch made from donated human umbilical cord tissue to repair spina bifida while the baby is still in the womb. Surgeons use a tiny camera to place the patch over the spinal opening, aiming to protect the nerves and reduce problems after birth. The trial includes 50 pregnant women carrying a baby with spina bifida.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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The University of Texas Health Science Center at Houston
Houston, Texas, 77030, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cryopreserved human umbilical cord allograft (NEOX Cord 1K®)
What this could lead to
If successful, this could offer a less invasive way to repair spina bifida before birth, potentially reducing nerve damage and the need for postnatal surgeries.
What could go wrong
This is an early-stage study with only 50 participants, so results may not apply to everyone. The procedure carries risks like preterm labor or infection, and the patch may not seal properly.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.