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Leg artery tube could help paramedics save cardiac arrest patients

NCT ID NCT07596446

Knowledge-focused Sponsor: Emergency Medical Service, Prague Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether paramedics can safely place a small tube in the leg artery of people having a cardiac arrest outside the hospital. The tube allows continuous blood pressure monitoring, which may help doctors give the right amount of medication to keep the heart pumping. The goal is to see if this approach is feasible and safe, and whether it can prevent another cardiac arrest during transport.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \* Non-traumatic out-of-hospital cardiac arrest (OHCA). Patients meeting criteria for one of the following clinical scenarios: Group A - ECPR-like group: * Refractory cardiac arrest, including cardiac arrest occurring in the presence of the EMS crew. * Age 18-70 years. * Effective bystander cardiopulmonary resuscitation. * Initial rhythm of ventricular fibrillation (VF), pulseless ventricular tachycardia (pVT), or pulseless electrical activity (PEA). Group B - post-ROSC group: * Return of spontaneous circulation (ROSC) after non-traumatic OHCA. * Age 18-70 years. Exclusion Criteria: * Trauma as the probable primary cause of cardiac arrest. * Known severe comorbidity, including: * terminal stage of incurable disease (advanced malignancy, advanced dementia, terminal pulmonary disease, terminal heart failure, or palliative care status), * established do-not-resuscitate (DNR) status, * severe pre-existing neurological disability (CPC 3 or CPC 4), * known severe peripheral arterial disease or known occlusion of lower limb arteries, * suspected pulmonary embolism with indication for thrombolytic therapy, * known severe hematological disease associated with severe thrombocytopenia, * morbid obesity. * Known or suspected pregnancy.

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Conditions

The condition(s) this trial relates to.

cardiac arrest cardiogenic shock Death, Sudden, Cardiac Out-of-Hospital Cardiac Arrest sudden cardiac arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiogenic shock acute Out-of-hospital cardiac arrest (OHCA) Sudden cardiac arrest

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • EMS Prague

    RECRUITING

    Prague, 10100, Czechia

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