New feeding strategy may cut pneumonia risk in severe stroke patients
NCT ID NCT07630090
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways of feeding patients with severe ischemic stroke who have trouble swallowing. The goal is to see if feeding through a tube placed past the stomach (post-pyloric) reduces the chance of developing pneumonia compared to standard stomach feeding. About 174 adults will take part, and researchers will track pneumonia cases within the first week.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 174 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years * Diagnosis of severe ischemic stroke, with NIHSS score \> 16 \[15-16\] * Confirmed dysphagia via swallowing assessment (Kubota Water Swallowing Test ≥ grade 3, or confirmed aspiration risk by FEES/VFSS) * Time from onset to enrollment ≤ 72 hours * Expected survival ≥ 7 days * Non-mechanically ventilated patients * Signed informed consent from patient or legal representative. Exclusion Criteria: * Diagnosed with pneumonia upon admission * High risk of gastrointestinal bleeding or perforation * Intestinal obstruction or gastrointestinal obstruction * Severe liver or kidney dysfunction * Advanced malignant tumor * Pregnancy or breastfeeding * Refusal to participate in the study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Jinling Hospital, Medical School of Nanjing University, Nanjing
Nanjing, Jiangsu, 210002, China
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Other studies related to the condition(s) this trial covers.
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