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Poop pills could tame IBD in Drug-Resistant patients

NCT ID NCT07149441

First seen Sep 30, 2025 · Last updated Jun 22, 2026 · Updated 41 times

Summary

This study tests whether fecal microbiota transplant (FMT) capsules, taken alongside standard biologic therapy, can improve symptoms and gut health in people with inflammatory bowel disease (Crohn's or ulcerative colitis). 94 patients who did not get better with biologics alone will receive either FMT capsules plus biologics or biologics alone. Researchers will track remission rates and safety over 52 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shanghai Tenth People's Hospital

    Shanghai, Shanghai Municipality, China

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

fecal microbiota transplant capsules

What this could lead to

If it works, this could offer a new way to improve symptoms and gut health for people with inflammatory bowel disease who haven't responded to standard treatments.

What could go wrong

This is a small, early-stage study with no placebo group, so results may not be conclusive. The treatment involves transplanting donor stool, which carries unknown long-term risks.

Conditions

The condition(s) this trial relates to.

inflammatory bowel disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.