New rule could help spot dangerous infections in kids after chemo
NCT ID NCT03434795
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new decision rule to help doctors tell which children with fever and low white blood cells after chemotherapy are at high risk for a serious infection. Researchers looked at 1,900 children aged 1 to 18 with cancer or blood disorders. The goal was to see if the rule works well across many hospitals so doctors can treat kids more safely.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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1,900 people
The number who actually took part.
- Start date
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May 2012
- Finished
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May 2017
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patient with hematology or cancer who consults for febrile neutropenia post-chemotherapy
- Ages
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1 year to 18 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Child aged 1 to 18 years * Child with hematology or cancer * Child with a febrile neutropenia post-chemotherapy * Child with social security * No opposition from the child and/or parents, in case of absence, the holder of the parental authority present, can consent, alone, to the participation of the unemancipated minor. Exclusion Criteria: * Febrile neutropenia at diagnosis of tumor disease * Child with palliative care * Child having had a hematopoietic stem cell allo-graft in the preceding year * Febrile neutropenia immediately post auto-transplant * Antibiotherapy prior to admission * Initial care in a non-investigative center.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hôpital Jeanne de Flandre - CHRU de Lille
Lille, France