Fatty acid intake linked to colon cancer risk in new study
NCT ID NCT01966081
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether eating certain fats (polyunsaturated fatty acids) is linked to colorectal cancer risk. Researchers measured fatty acids in fat tissue and blood samples from 551 people with and without colorectal cancer. The goal was to find reliable biomarkers that could help understand diet's role in cancer risk.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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551 people
The number who actually took part.
- Started
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Sep 2008
- Finished
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Jun 2011
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: CASES * Patients aged ≥ 45 years * with a first recently-diagnosed colorectal cancer * due to undergo elective surgical resection with curative intent (in practice, stage I, II, III or IV if there was only one hepatic nodule that was resected with curative intent) in one of the 5 following digestive surgery units: CHU de Dijon, CHU de Nancy, CHU de Strasbourg, CHU de Reims et CHU and Besançon. * who have given their informed consent CONTROLS * Patients aged ≥ 45 years * due to undergo surgery for a benign abdominal disease (sigmoid diverticulitis, appendectomy, hiatal hernia …) * matched for abdominal site with cases for age (± 3 years), sex and hospital * Who have given their informed consent Exclusion Criteria: CASES * pre-operative anticancer treatment (chemo or radiotherapy) * existence of visceral metastases except a single hepatic nodule resected with curative intent * familial adenomatous polyposis and HNPCC syndrome (when suspected: inclusion after complementary tumor phenotype study: screening for microsatellite instability and/or immunohistochemistry study of the expression of DNA mismatch repair proteins. * known inflammatory disease of the intestine (ulcerative colitis, Crohn's disease) * personal history (recent or not) of colorectal cancer * emergency treatment for the presenting complication (perforation, occlusion…) * significant modification in dietary habits during the previous three months * other evolving neoplastic disease * psychic state incompatible with understanding the modalities and the aims of the study (notably patients under guardianship) * pregnant or breast-feeding women CONTROLS * personal history of cancer or adenomatous colorectal polyps, * emergency intervention * known inflammatory disease of the intestine (ulcerative colitis, Crohn's disease) * personal history (recent or not) of colorectal cancer * emergency treatment for the presenting complication (perforation, occlusion…) * significant modification in dietary habits during the previous three months * evolving neoplastic disease * psychic state incompatible with understanding the modalities and the aims of the study (notably patients under guardianship) * pregnant or breast-feeding women
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU Dijon
Dijon, 21079, France
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CHU Jean Minjoz
Besançon, 25030, France
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Hôpital Hautepierre
Strasbourg, 67200, France
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Hôpital Robert Debré
Reims, 51092, France
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Hôpital de BRABOIS
Vandœuvre-lès-Nancy, 54511, France