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2,000 MS patients sought for landmark fatigue study

NCT ID NCT06441617

Symptom relief Sponsor: Accelerated Cure Project for Multiple Sclerosis Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This study tests two online programs designed to help people with multiple sclerosis (MS) understand and manage their fatigue. Researchers will enroll 2,000 adults with MS across the U.S., including veterans, and compare the programs to usual care alone. The goal is to find practical, accessible ways to reduce fatigue and improve daily life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 2,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2024

Expected to finish

Sep 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

22 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Informed consent by person with MS * Living in the US * Age ≥ 22 * Confirmed diagnosis of MS by a physician, who is a neurologist or has access to a neurologist's statement of diagnosis * Fatigue Severity Scale score at or above eligibility threshold * Fluent in English * Willingness to engage in self-administration of an online intervention for 24 weeks and complete follow-up assessments * Access to the internet and e-mail with a compatible device (smartphone, computer, or tablet) * No MS relapse / no steroid treatment in the 4 weeks prior to answering the screening questionnaire (self-reported) * No disease-modifying therapeutic (DMT) started in the 4 weeks prior to answering the screening questionnaire (self-reported) Exclusion Criteria: * Unwilling or unable to consent * Refusal to saving, processing and forwarding of pseudonymized data * Concurrent participation in another interventional trial

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Conditions

The condition(s) this trial relates to.

Fatigue multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Fatigue Multiple sclerosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Baltimore VA Medical Center

    Baltimore, Maryland, 21201, United States

  • Nashville VA Medical Center

    Nashville, Tennessee, 37212, United States

  • Portland VA Medical Center

    Portland, Oregon, 97239, United States

  • Seattle VA Medical Center

    Seattle, Washington, 98108, United States

  • Washington VA Medical Center

    Washington D.C., District of Columbia, 20422, United States

  • iConquerMS

    Waltham, Massachusetts, 02451, United States

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