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Squat science: new way to gauge muscle fatigue discovered!

NCT ID NCT07307963

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether measuring how fast you can lift a weight (velocity) and how much weight you can handle (load) can show how tired your muscles get from doing squats. Twenty-eight men who regularly lift weights did different squat routines, and their speed and load were checked before and after. The goal was to see if these simple measurements could be a practical tool for athletes and trainers to monitor fatigue.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

28 people

The number who actually took part.

Started

May 2024

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Twenty-eight physically trained males, with an average age of 23.3 years (standard deviation \[SD\]: 3.0 years; range: 20-36 years), willingly enrolled in this research endeavor. The participants exhibited a mean body mass of 78.1 kg (SD: 9.3 kg), a body height of 177.2 cm (SD: 3.3 cm), and a one-repetition maximum (1RM) for smith-machine squat (SMS) exercise of 150.9 kg (SD: 12.5 kg). All subjects possessed prior RT experience, averaging 5.0 years (SD: 2.6 years), and demonstrated proficiency in executing the SMS exercise during the familiarization session.

Ages

18 to 35 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Healthy males aged 18-40 years. Resistance-trained (minimum 2 years of regular lower-body resistance training and ≥2 sessions/week). Able to perform a proper smith-machine back squat with correct technique. 1-RM smith-machine squat measurable and ≥ bodyweight (or specify threshold used in study). No musculoskeletal injury of lower limbs or back in the past 6 months. Not using performance-enhancing drugs or anabolic steroids for the past 12 months. Willing and able to attend all testing and training sessions and provide written informed consent. Exclusion Criteria: Any cardiovascular, pulmonary, metabolic, or neurological disease contraindicating intense exercise. Recent (≤6 months) lower-extremity or spinal surgery or acute injury. Current musculoskeletal pain or injury that limits squat performance. Use of medications that affect neuromuscular performance (e.g., systemic corticosteroids) or stimulant drugs. Regular participation in structured lower-body rehabilitation programs. Failure to complete familiarization or preliminary 1-RM testing. Inability or unwillingness to provide informed consent or follow study procedures.

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Conditions

The condition(s) this trial relates to.

Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • İstanbul Gelişim Üniversity

    Istanbul, avcılar, 34310, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.