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Can tired muscles change how you feel pain?

NCT ID NCT07577622

Knowledge-focused Sponsor: Universidad Miguel Hernandez de Elche Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how different levels of fatigue from leg strength exercises affect pain perception in healthy adults. 27 participants will do three sessions of leg extensions with varying fatigue levels. Researchers will measure pain sensitivity, strength, and perceived effort to understand the link between exercise fatigue and pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Strength training (leg extension machine)
What this could lead to
If successful, this could help design better exercise programs for pain management.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to people with chronic pain. The effect on pain is temporary and not a treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 27 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy, asymptomatic subjects * Being physically active Exclusion Criteria: * Experiencing episodes of acute pain in any part of the body. * Having chronic pain or a recent history of chronic pain conditions considered resolved within the last 6 months. * Having a serious illness or inability to perform moderate or intense physical activity. * Having taken pain relievers, fever reducers, anti-inflammatory drugs (NSAIDs), steroids, opioids, or similar medications in the 24 hours before a session. * Having consumed alcohol or other psychoactive substances, caffeine, or other stimulants in the 24 hours before a session. * Having performed tiring physical activity or strength exercise in the 24 hours before a session.

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Conditions

The condition(s) this trial relates to.

Fatigue Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise induced hypoalgesia Healthy adult volunteer

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Universidad Miguel Hernández

    Alicante, ALICANTE, 03550, Spain

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