Can tired muscles change how you feel pain?
NCT ID NCT07577622
First seen May 13, 2026 · Last updated Jun 23, 2026 · Updated 5 times
Summary
This study looks at how different levels of fatigue from leg strength exercises affect pain perception in healthy adults. 27 participants will do three sessions of leg extensions with varying fatigue levels. Researchers will measure pain sensitivity, strength, and perceived effort to understand the link between exercise fatigue and pain relief.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Universidad Miguel Hernández
Alicante, ALICANTE, 03550, Spain
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Strength training (leg extension machine)
What this could lead to
If successful, this could help design better exercise programs for pain management.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to people with chronic pain. The effect on pain is temporary and not a treatment.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.