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Can a Patient's own fat keep fingers moving after fracture surgery?

NCT ID NCT07815444

Symptom relief Sponsor: Jeroen Bosch Ziekenhuis Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

After surgery for a broken finger bone, scar tissue can form around tendons and make the finger stiff. Researchers are testing whether injecting a small amount of the patient's own fat around the repaired bone or during scar-release surgery helps the finger move better. In this double-blinded trial, 130 adults with a proximal phalanx fracture or related tenolysis receive either the fat injection or a saltwater injection. The team measures finger motion, hand function, and complications over six months.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
micronised fat graft (lipofilling) taken from the patient's own belly fat
What this could lead to
If it works, surgeons could add a simple fat injection during hand fracture surgery to help patients regain finger movement and avoid a second operation.
What could go wrong
The trial is early and the evidence for fat grafting in hand surgery is limited. Fat may not survive or may not prevent scar tissue, and harvesting fat adds a small procedure on the belly with its own discomfort and risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 130 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Jul 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18-65 years * Indication for one of the following surgical procedures: * ORIF due to a single radiologically proven P1 fracture * Secondary tenolysis due to limited digital function after former operative treatment of a P1 fracture * Able to read and speak Dutch * Mentally competent Exclusion Criteria: * Aged below 18 or above 65 years * Concomitant tendinous or neurovascular injuries * Prior surgical interventions of the affected digit; other than operative fracture fixation in case of tenolysis * Prior pathology or surgical interventions of the contralateral digit * Less than 3 months of competent hand therapy in case of secondary tenolysis * A known psychiatric condition * A known systemic disease that will impair wound healing (e.g. diabetes mellitus, known atherosclerosis with an event that required hospitalization, collagen diseases, diseases of the skin, HIV). * Prednisone or other immunotherapy * Smoking * Pregnancy or active child wish

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Conditions

The condition(s) this trial relates to.

bone fracture Tissue Adhesions

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adhesions Hand fractures Tenolysis

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • Jeroen Bosch Ziekenhuis

    's-Hertogenbosch, North Brabant, 5223 GZ, Netherlands

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