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Which liposuction device keeps fat cells alive?

NCT ID NCT07820397

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Researchers compare two ultrasound-assisted liposuction devices, AYON and VASER, and two fat-removal methods, vacuum and peristaltic pump, to see how each affects the health of harvested fat tissue. Thirty adults planning elective liposuction in two or more body areas take part. Each person serves as their own control, with fat samples taken from matched areas on opposite sides of the body. The study measures how many fat cells survive and other tissue features such as cell density and fat composition.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Ultrasound-assisted liposuction devices (AYON and VASER) and fat-removal methods (vacuum and peristaltic pump)
What this could lead to
If one device or method preserves more living fat cells, doctors could choose it when harvested fat is meant for grafting or fat-derived cell therapies.
What could go wrong
This is a small, 30-person comparison of lab measures, not patient outcomes. Differences in cell viability may not translate into better grafting results, and the findings may not apply to other surgeons or body areas.
Why investors are watching

Apyx Medical sells liposuction devices, and this trial compares fat tissue harvested with ultrasound-assisted and power-assisted liposuction to see which method yields better quality tissue. For a micro-cap company, a readout that favors its own technology would give sales staff and surgeons a concrete reason to choose its devices over rivals.

If it works: If the data show Apyx's approach preserves fat cells better, the company could use that finding to support marketing and surgeon training, which may help it win accounts.

If it fails: This is a small 30-participant study, and it may not show a clear difference between methods. If results favor a competing technique or the data are mixed, the company gains little from the readout, and trials like this often fail to produce a decisive answer.

AI-written from the trial record. Speculative, and not investment advice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 30 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2026

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female aged 30 to 65 years, inclusive. * Planned elective liposuction/body contouring procedure involving two or more anatomical areas (e.g., arms, abdomen, flanks, thighs, and/or back) with sufficient distribution to permit collection of paired adipose tissue samples from contralateral or anatomically matched treatment areas. * Investigator determines the subject is an appropriate candidate for the planned procedure and study participation. * Adequate adipose tissue is present to permit collection of required paired fat samples without impacting the planned surgical outcome. * Able to understand and sign the informed consent form. * Willing and able to comply with study requirements. * If applicable, female subjects of childbearing potential must have a negative urine pregnancy test on the day of procedure. Exclusion Criteria: * Prior liposuction or surgical intervention in the planned treatment areas that, in the opinion of the investigator, may affect adipose tissue characteristics or study assessments. * Prior treatment of the planned treatment areas with energy-based devices (e.g., ultrasound, radiofrequency, laser) that, in the opinion of the investigator, may affect adipose tissue characteristics or study assessments. * Significant skin laxity, fibrosis, scarring, or other abnormal tissue characteristics in the planned treatment areas that could impact fat harvest quality or comparability between sites. * Current smoker or use of nicotine-containing products within 4 weeks prior to the procedure. * Known metabolic or systemic conditions that may affect adipose tissue biology or wound healing, including but not limited to: * uncontrolled diabetes mellitus * significant vascular disease * connective tissue disorders * Use of medications known to significantly affect fat metabolism, tissue healing, or inflammatory response, including: * chronic systemic corticosteroids * immunosuppressive therapies * GLP-1 receptor agonists (e.g., semaglutide, tirzepatide) within 4 weeks prior to the procedure * Active local or systemic infection at the time of the procedure. * Known coagulopathy or use of anticoagulant therapy that cannot be safely discontinued prior to surgery. * Pregnant or breastfeeding subjects. * Body mass index (BMI) outside the range of 20-35 kg/m², inclusive. * Inadequate adipose tissue volume or distribution to permit paired sample collection from contralateral or anatomically matched areas. * Participation in another interventional clinical study that, in the opinion of the investigator, could interfere with study endpoints. * Any condition that, in the opinion of the investigator, would make the subject unsuitable for participation or could confound study results.

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As listed by the trial registrant

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How to take part

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  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    2 sites. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Mentor Plastic Surgery

    RECRUITING

    Concord, Ohio, 44077, United States

  • Pearl Plastic Surgery

    RECRUITING

    Olympia, Washington, 98506, United States

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