Which liposuction device keeps fat cells alive?
NCT ID NCT07820397
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Researchers compare two ultrasound-assisted liposuction devices, AYON and VASER, and two fat-removal methods, vacuum and peristaltic pump, to see how each affects the health of harvested fat tissue. Thirty adults planning elective liposuction in two or more body areas take part. Each person serves as their own control, with fat samples taken from matched areas on opposite sides of the body. The study measures how many fat cells survive and other tissue features such as cell density and fat composition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ultrasound-assisted liposuction devices (AYON and VASER) and fat-removal methods (vacuum and peristaltic pump)
- What this could lead to
- If one device or method preserves more living fat cells, doctors could choose it when harvested fat is meant for grafting or fat-derived cell therapies.
- What could go wrong
- This is a small, 30-person comparison of lab measures, not patient outcomes. Differences in cell viability may not translate into better grafting results, and the findings may not apply to other surgeons or body areas.
Why investors are watching
Apyx Medical sells liposuction devices, and this trial compares fat tissue harvested with ultrasound-assisted and power-assisted liposuction to see which method yields better quality tissue. For a micro-cap company, a readout that favors its own technology would give sales staff and surgeons a concrete reason to choose its devices over rivals.
If it works: If the data show Apyx's approach preserves fat cells better, the company could use that finding to support marketing and surgeon training, which may help it win accounts.
If it fails: This is a small 30-participant study, and it may not show a clear difference between methods. If results favor a competing technique or the data are mixed, the company gains little from the readout, and trials like this often fail to produce a decisive answer.
AI-written from the trial record. Speculative, and not investment advice.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2026
- Expected to finish
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Apr 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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30 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female aged 30 to 65 years, inclusive. * Planned elective liposuction/body contouring procedure involving two or more anatomical areas (e.g., arms, abdomen, flanks, thighs, and/or back) with sufficient distribution to permit collection of paired adipose tissue samples from contralateral or anatomically matched treatment areas. * Investigator determines the subject is an appropriate candidate for the planned procedure and study participation. * Adequate adipose tissue is present to permit collection of required paired fat samples without impacting the planned surgical outcome. * Able to understand and sign the informed consent form. * Willing and able to comply with study requirements. * If applicable, female subjects of childbearing potential must have a negative urine pregnancy test on the day of procedure. Exclusion Criteria: * Prior liposuction or surgical intervention in the planned treatment areas that, in the opinion of the investigator, may affect adipose tissue characteristics or study assessments. * Prior treatment of the planned treatment areas with energy-based devices (e.g., ultrasound, radiofrequency, laser) that, in the opinion of the investigator, may affect adipose tissue characteristics or study assessments. * Significant skin laxity, fibrosis, scarring, or other abnormal tissue characteristics in the planned treatment areas that could impact fat harvest quality or comparability between sites. * Current smoker or use of nicotine-containing products within 4 weeks prior to the procedure. * Known metabolic or systemic conditions that may affect adipose tissue biology or wound healing, including but not limited to: * uncontrolled diabetes mellitus * significant vascular disease * connective tissue disorders * Use of medications known to significantly affect fat metabolism, tissue healing, or inflammatory response, including: * chronic systemic corticosteroids * immunosuppressive therapies * GLP-1 receptor agonists (e.g., semaglutide, tirzepatide) within 4 weeks prior to the procedure * Active local or systemic infection at the time of the procedure. * Known coagulopathy or use of anticoagulant therapy that cannot be safely discontinued prior to surgery. * Pregnant or breastfeeding subjects. * Body mass index (BMI) outside the range of 20-35 kg/m², inclusive. * Inadequate adipose tissue volume or distribution to permit paired sample collection from contralateral or anatomically matched areas. * Participation in another interventional clinical study that, in the opinion of the investigator, could interfere with study endpoints. * Any condition that, in the opinion of the investigator, would make the subject unsuitable for participation or could confound study results.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Mentor Plastic Surgery
RECRUITINGConcord, Ohio, 44077, United States
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Pearl Plastic Surgery
RECRUITINGOlympia, Washington, 98506, United States
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