Could a drug combo replace transplant for myeloma patients?
NCT ID NCT06974786
First seen Nov 06, 2025 · Last updated May 23, 2026 · Updated 23 times
Summary
This study tests whether a combination of two drugs (elranatamab and daratumumab) can work as well as or better than a stem cell transplant followed by maintenance therapy for people newly diagnosed with multiple myeloma. About 100 participants will be randomly assigned to one of the two treatment paths. The main goal is to see which approach leads to undetectable levels of cancer in the bone marrow, a sign of deep remission.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Colorado Blood Cancer Institute
RECRUITINGDenver, Colorado, 80218, United States
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Medical College of Wisconsin
RECRUITINGMilwaukee, Wisconsin, 53226, United States
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Oncology Hematology Care
RECRUITINGCincinnati, Ohio, 45242, United States
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SCRI Oncology Partners
RECRUITINGNashville, Tennessee, 37203, United States
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The Ohio State University- The James Cancer Hospital and Solove Research Institute
RECRUITINGColumbus, Ohio, 43210, United States
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35294, United States
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
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University of North Carolina
RECRUITINGChapel Hill, North Carolina, 27599, United States
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University of Texas Southwestern
RECRUITINGDallas, Texas, 75390, United States
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University of Wisconsin Clinical Science Center
RECRUITINGMadison, Wisconsin, 53792, United States
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Virginia Oncology Associates
RECRUITINGNorfolk, Virginia, 23502, United States
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Conditions
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