New drug combo challenges stem cell transplant in multiple myeloma trial

NCT ID NCT06974786

Recruiting now Disease control Sponsor: SCRI Development Innovations, LLC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a combination of two drugs (elranatamab and daratumumab) can work as well as or better than a stem cell transplant for people newly diagnosed with multiple myeloma. About 100 adults who have already had initial treatment will be randomly assigned to one of two groups. The goal is to see which approach better eliminates cancer cells deep in the bone marrow.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE MYELOMA (MM) MULTIPLE MYELOMA, NEWLY DIAGNOSED

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Colorado Blood Cancer Institute
RECRUITING

Denver, Colorado, 80218, United States

Contact
Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States

Contact
Oncology Hematology Care
WITHDRAWN

Cincinnati, Ohio, 45242, United States
SCRI Oncology Partners
RECRUITING

Nashville, Tennessee, 37203, United States

Contact
The Ohio State University- The James Cancer Hospital and Solove Research Institute
RECRUITING

Columbus, Ohio, 43210, United States

Contact
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294, United States

Contact
University of Iowa
RECRUITING

Iowa City, Iowa, 52242, United States

Contact
University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27599, United States

Contact
University of Texas Southwestern
RECRUITING

Dallas, Texas, 75390, United States

Contact
University of Wisconsin Clinical Science Center
RECRUITING

Madison, Wisconsin, 53792, United States

Contact
Virginia Oncology Associates
RECRUITING

Norfolk, Virginia, 23502, United States

Contact

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