MRI scans may reveal hidden clues to myeloma relapse risk
NCT ID NCT07746232
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study is looking at whether a special type of whole-body MRI can help predict how well people with multiple myeloma will do after a stem cell transplant. The MRI measures changes in bone marrow and fat content in the bones, which might indicate if the cancer is more likely to come back. By following patients over time, researchers hope to see if these imaging markers can identify those who need closer monitoring or different treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Diffusion-weighted whole-body MRI (DW-MRI) and fat fraction measurement
- What this could lead to
- If successful, this could establish MRI as a reliable tool to predict which myeloma patients are at higher risk of relapse after transplant, enabling more personalized follow-up and treatment.
- What could go wrong
- This is an observational study, so it won't test a new treatment. The predictive value of the MRI measures is not yet proven, and results may not change current practice without further validation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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A.O. Spedali Civili di Brescia
Brescia, Italy
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A.O.U. Maggiore della Carità
Novara, Italy
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A.O.U. di Bologna - Policlinico S. Orsola Malpighi
Bologna, Italy
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ASL Roma 1
Rome, Italy
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I.R.C.C.S. Ospedale S. Raffaele
Milan, Italy
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IRCCS Istituto Tumori "G. Paolo II - U.O.C. Ematologia e Terapia Cellulare
Bari, Italy
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Istituto Oncologico Veneto IRCCS - UOC Oncoematologia
Castelfranco Veneto, Italy
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Ospedale Classificato Valduce
Como, Italy
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Ospedale Niguarda
Milan, Italy
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Policlinico S. Matteo Fondazione IRCCS
Pavia, Italy
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