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Can a new antibiotic outperform standard care for pneumonia?

NCT ID NCT06804096

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This trial compares the antibiotic faropenem to a standard combination of co-amoxiclav and clarithromycin in adults with community-acquired bacterial pneumonia. Participants are randomly assigned to one of two treatment groups for seven days, then followed for four weeks. The study measures how well each treatment cures the infection and tracks any side effects, aiming to see if faropenem could be a valuable option in regions with limited treatment choices.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
faropenem
What this could lead to
If faropenem works as well as or better than standard treatments, it could offer a new, effective antibiotic option for bacterial pneumonia, especially in regions with limited alternatives.
What could go wrong
This is a single trial in one country, and faropenem may not prove superior to existing antibiotics. As with any antibiotic, there are risks of side effects and the potential for bacterial resistance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

129 people

The number who actually took part.

Started

Feb 2025

Finished

Jan 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male or female patients aged between 18 to 65 years. * Have an acute illness (less than or equal to 7 days duration) with any of the following signs and symptoms consistent with a lower respiratory tract infection (new or worsening): 1. Fever (body temperature \> 38.0 °C (100.4 °F) measured orally) 2. Shortness of breath 3. New onset or increased cough with or without sputum production. 4. Chest pain. * Have radiographically documented bacterial pneumonia: 1. Infiltrates in a unilateral, lobar distribution 2. Diffuse opacities or white condensed area 3. The alveoli fill with white inflammatory fluid Exclusion Criteria: * Patients with severe pneumonia (Clinical \& Radiological Assessment) * Patients with suspicion of viral pneumonia (bilateral, patchy opacities, etc., in chest radiography.) * Patients with suspicion of nosocomial pneumonia, aspiration pneumonia, etc. * History of hypersensitivity, known or suspected contraindications, or intolerance to any of the study drugs. * Intake of an antibiotic within the last 48 hours before study admission. * History of hospitalization within the last 28 days. * Patients in pregnancy and lactational state. * Patients with Renal impairment (screening eGFR \< 30mL/min). * Significant hepatic impairment (Alanine aminotransferase \> three times the upper limit of normal). * Serious diseases that affect the immune system, such as Acquired Immunodeficiency Syndrome (AIDS), cancer, etc. * Patients who are taking steroid medications, at least 20 mg daily dose of prednisolone (or equivalent doses of other glucocorticoids). * Patients who are accepting chemotherapy or anti-cancer therapy or plan to receive such treatment during the trial or six months prior to enrollment. * Had epilepsy, stroke, or other central nervous system disorders or uncontrolled psychiatric history.

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Conditions

The condition(s) this trial relates to.

bacterial pneumonia Community-Acquired Pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Popular Medical College & Hospital

    Dhaka, Dhaka Division, 1205, Bangladesh

  • Shaheed Suhrawardy Medical College & Hospital

    Dhaka, Dhaka Division, 1205, Bangladesh

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