Laser plus injection may improve scar healing
NCT ID NCT07472192
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding PDRN injections to standard CO2 laser therapy helps facial scars heal better and look less noticeable. It includes 36 adults with recent scars from cuts or surgery. The goal is to see if the combination is safer and more effective than laser alone.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Polydeoxyribonucleotide (PDRN) injections
- What this could lead to
- If it works, this could offer a more effective way to reduce facial scars and speed up healing after injury or surgery.
- What could go wrong
- This is a small, early-phase trial with only 36 people. The added benefit of PDRN may be minimal, and there is a risk of allergic reaction to PDRN.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age Limitations: Participants must be between 18 and 50 years of age. * Recently cut wounds or surgical scars from about (1-6 months). * Consent to Participate: Willingness to provide informed consent and engage in all aspects of the study. Exclusion Criteria: * Pregnancy or breastfeeding at the time of study. * Known allergy to PDRN. * Medication use that could affect wound healing or inflammation, such as: * Isotretinoin. * Anticancer drugs. * High-dose corticosteroids. * Anticoagulants. * Uncontrolled medical diseases (e.g., unstable diabetes, cardiac conditions).
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Misr University for Science and Technology
RECRUITINGGiza, Egypt
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