Can a simple face injection boost Well-Being after breast cancer?
NCT ID NCT07425548
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test whether hyaluronic acid injections in the face can improve appearance and quality of life in women who have completed breast cancer treatment. The researchers plan to enroll 22 women aged 18 to 50 who became menopausal due to chemotherapy or hormone therapy. Participants will receive up to 3 ml of hyaluronic acid, and their facial appearance, quality of life, and side effects will be measured using a standard questionnaire.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- hyaluronic acid injections
- What this could lead to
- If it works, this could offer a safe, minimally invasive way to improve skin quality and self-esteem in breast cancer survivors.
- What could go wrong
- This is a very small, early study with only 22 participants and no control group. Results may not apply to all survivors, and risks like bruising or infection are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 22 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Women ≥ 18 years old and ≤ 50 years old. 2. Non-menopausal status at time of diagnosis of breast cancer (self-reporting). 3. Patient with breast cancer (uni or bilateral): 1. treated at the Institut Bergonié by chemotherapy (+/- targeted/immunotherapy) and surgical treatment (conservative or not) and/or hormone therapy and/or radiotherapy 2. who completed their treatment at least 6 months ago including end of treatment with Herceptin but with the exception for ongoing hormone therapy 3. in complete remission 4. Non-immunosuppressed patient. 5. Voluntarily signed and dated written informed consent prior to any study specific procedure. 6. Patient affiliated to a social security in compliance with Article 1121-11 of the French Public Health Code. Exclusion Criteria: 1. Patients with a history of or declared autoimmune disease or immune system deficiency or undergoing immunosuppressive treatment. A 6-month washout is required. 2. Patients undergoing or planning to undergo peeling treatment or laser/ultrasound-based or botox treatment or hyaluronic acid injections during the study or having had one of these treatments in the 6 months preceding the study. 3. Patients showing cutaneous disorders, inflammation or infection (acne, herpes labialis, scars…) at the treatment site or near to this site. 4. Patients having a known hypersensibility to lidocaine and/or amide local anaesthetic agents or hyaluronic acid and/or proteins from gram-positive bacteria, or with a history of severe allergy or anaphylactic shock. 5. Patients with a history of streptococcal disease (recurrent sore throat, rheumatic fever) 6. Patients with autoimmune or cardiac diseases (i.e. heart conduction disorders) and/or undergoing treatment for heart diseases (beta-blockers). 7. Patients with hepatocellular insufficiency and/or undergoing treatment for liver disease. 8. Patients suffering from epilepsy not controlled by a treatment or porphyria. 9. Patients with a tendency to develop hypertrophic scars. 10. Patients with severe, ongoing and/or uncontrolled disease that may pose a health risk to the patient during the study and/or may have an impact on the study assessments. 11. Patients receiving or planning to receive high dose Vitamin E, aspirin, anti-inflammatories, or anti-coagulant during the week preceding each injection 12. Patients receiving any long-term medical treatment or any treatment that, in the opinion of the clinical investigator, may interfere with test results or put the patient at undue risk. 13. Patients under guardianship/tutorship. 14. Pregnant women or breastfeeding mothers.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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