New PET technique may solve brain scan puzzle
NCT ID NCT05762172
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether an early, quick PET scan using F-DOPA can help doctors tell the difference between a brain tumor coming back and damage from radiation therapy. Eight patients who already needed a PET scan for their brain metastases took part. The goal was to see if measuring tracer activity within the first few minutes after injection could improve diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- 18F-FDOPA (a radioactive tracer used in PET scans)
- What this could lead to
- If successful, this could provide a more accurate way to distinguish between cancer recurrence and radiation-induced tissue damage in the brain, helping guide treatment decisions.
- What could go wrong
- This is a very small pilot study with only 8 participants, so results may not apply broadly. The technique is still experimental and needs much larger studies to confirm its usefulness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
8 people
The number who actually took part.
- Started
-
Feb 2022
- Finished
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Nov 2024
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient referred for cerebral 18F-FDOPA PET examination prescribed as part of his usual medical care for brain metastasis * Age ≥ 18 years old * Affiliation to a social security program * Ability of the subject to understand and express opposition Exclusion Criteria: * Age under 18 * Person under guardianship or curators * Pregnant woman
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CHU Amiens
Amiens, Picardie, 80054, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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