Eye-Tracking tech could spot MS severity without needles
NCT ID NCT06283524
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether eye movements can help measure how severe multiple sclerosis (MS) is and how well the brain is working. Researchers tracked the eyes of 200 people with MS while they did tasks on a screen. The goal was to train computer programs to find patterns in eye movements that match standard disability and thinking tests, which could lead to a simple, non-invasive way to monitor MS.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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200 people
The number who actually took part.
- Started
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Mar 2024
- Finished
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Mar 2026
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Our target sample size for the MS group is up to 100 patients. Eligible patients with MS will be selected and categorized based on their EDSS score.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Able to provide informed consent * Aged 18 years or older at the time of enrollment * Able to read in either French or English * Able to read the oculomotor task on-screen instructions at the testing distance (45cm) with or without corrective lenses * Confirmed diagnosis of MS as per the Macdonald criteria, irrespective of MS subtype (relapsing-remitting (RRMS), secondary-progressive (SPMS), primary-progressive (PPMS), and progressive-relapsing (PRMS)) * Neurologist-determined EDSS score between 1.0-8.0 Exclusion Criteria: * Evidence or medical history of psychiatric issues, which are known to also affect movements and oculomotor control * Presence of comorbid neurological conditions to avoid eye movement anomaly confounds (Strabismus, cranial nerve palsy, stroke-causing hemianopsia) * Diagnosis of macular edema or other pre-existing ocular conditions that would prevent a participant from performing the eye movement assessments * Having started a new prescription medication or having changed the dose of a medication known to influence ocular motor visual function (e.g. benzodiazepines, antipsychotics and anticonvulsants) within the past three months * Participants with non-disease related physical impairments to a leg, hand, or arm (e.g., broken bone or severe sprain) that would not allow completion of the assessments
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Genge Partners, Inc.
Montreal, Quebec, H4A 3T4, Canada
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Other studies related to the condition(s) this trial covers.
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