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Eye pressure shifts during ventilator weaning: what ICU doctors need to know

NCT ID NCT07188922

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 40 ICU patients on breathing machines to see how their eye pressure changed when they started breathing on their own. Researchers measured eye pressure non-invasively before and after the switch. The goal was to understand if the transition affects eye pressure, which could help protect patients with eye problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better understand how eye pressure changes during ventilator weaning, potentially leading to safer care for ICU patients with eye risks.
What could go wrong
This is a small, single-center observational study with only 40 participants. It does not test any treatment, so it cannot directly change practice. Results may not apply to all ICU patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

40 people

The number who actually took part.

Started

Sep 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients admitted to the intensive care unit of Elazığ Fethi Sekin City Hospital, Department of Anesthesiology and Reanimation, who are receiving invasive mechanical ventilation and undergoing clinically indicated weaning.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 85 years * Admitted to intensive care unit (ICU) and receiving invasive mechanical ventilation * Clinically scheduled for weaning and transition to spontaneous breathing * Able to undergo intraocular pressure (IOP) measurement before and after transition * Written informed consent obtained from the patient or legal representative Exclusion Criteria: * History of glaucoma, ocular hypertension, or previous eye surgery * Active ocular infection or trauma * Hemodynamic instability that prevents safe measurement * Inability to obtain reliable IOP measurements * Refusal of consent by patient or legal representative

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Elazığ Fethi Sekin City Hospital

    Elâzığ, Merkez, 23200, Turkey (Türkiye)

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