Eye surgery study could unlock secrets of blinding diseases
NCT ID NCT07260097
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is observing how blood flow at the back of the eye changes after a type of retinal detachment surgery called scleral buckling. Researchers hope these observations will help them better understand other eye diseases, such as age-related macular degeneration. The study will enroll 50 adults who are having this surgery for the first time.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could improve understanding of eye diseases like age-related macular degeneration, potentially leading to better treatments in the future.
- What could go wrong
- This is a small, early observational study, not testing a treatment. It may not lead to direct patient benefits or generalizable results.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
50 participants from the Singapore National Eye Centre.
- Ages
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21 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 21 years and above * Ability to provide informed consent * First occurrence of a retinal detachment in one eye, deemed to require SB surgery with or without vitrectomy and/or cataract surgery. * Clinically normal fellow eye (no previous intraocular surgery except for cataract extraction with lens implant, intraocular laser or injection procedures). Exclusion Criteria: * Affected eye undergoing vitreoretinal procedure other than an SB surgery with or without vitrectomy and/or cataract surgery. * Pregnant or nursing women * Persons who are unable to give informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Singapore Eye Research Institute
RECRUITINGSingapore, Singapore
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Other studies related to the condition(s) this trial covers.
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- AI eye scanner could speed up emergency referrals for vision loss