Inside the metabolic chamber: scientists probe extreme obesity
NCT ID NCT07613255
First seen Jun 26, 2026 · Last updated Sep 18, 2026 · Updated 3 times
Summary
This study will measure how the body uses energy and burns fat in 10 people with extreme obesity (BMI of 60 or higher). Participants will spend 23 hours in a special metabolic chamber and drink a labeled water to track energy use over a week. The goal is to better understand metabolism in this group, not to test a treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could improve understanding of how the body burns energy and fat in extreme obesity, potentially guiding future treatments.
- What could go wrong
- This is a very small, early observational study with only 10 participants, so results may not apply to everyone. It does not test any treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 10 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Oct 2026
An estimate. Start dates often move.
- Expected to finish
-
Apr 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The population for this study is individuals aged 18 to 80 years old who have a BMI greater than or equal to 60 kg/m2 who are willing to consume pre-prepared meals and are willing to have biospecimens and images stored for future use. The reason for seeking to evaluate this specific population is because individuals with extreme obesity possess high surgical and comorbidity risks, but there is a very small amount of research conducted in these individuals.
- Ages
-
18 to 80 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy male or female * Between 18 - 80 years of age * BMI ≥60 kg/m2 * Willing to consume pre-prepared meals * Willing to comply with the study procedures. * Willing to have biospecimens and images stored for future use. Exclusion Criteria: * Diabetic individuals with complications such as: * Diabetic eye disease requiring laser treatment * Diabetic nerve disease associated with foot ulcers or amputations * Diabetic vascular disease associated with gangrene or amputation * Diabetic kidney disease accompanied by a creatinine greater than 2.0 mg/dL * Individuals with prior gastrointestinal surgery except appendectomy or cholecystectomy * Individuals with untreated thyroid disease * Individuals with untreated or poorly controlled binge eating disorder, bulimia, substance abuse or dependence, mania, and psychosis. * Women who are pregnant, trying to become pregnant, or currently breastfeeding. * Individuals with major organ system failure like cirrhosis, hepatic insufficiency, portal hypertension, severe renal insufficiency or on dialysis, severe arterial insufficiency, dementia or the inability to give an informed consent. * Being unwilling to comply with the study procedures. * Not willing to have biospecimens and/or images stored for future research use.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Bmi>40 are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.