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New painkiller may cut opioid use after foot surgery

NCT ID NCT05494645

First seen May 12, 2026 · Last updated May 23, 2026 · Updated 3 times

Summary

This study tested whether adding a long-acting painkiller called Exparel to standard numbing injections can improve pain control and reduce the need for opioid pain pills after foot or ankle surgery. 248 adults having elective foot or ankle surgery took part. Researchers measured how long the block lasted and how many opioids patients used in the first few days after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • St. Luke's University Health Network

    Bethlehem, Pennsylvania, 18015, United States

Conditions

Explore the condition pages connected to this study.